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Hydrocodone: Overview and Key Information

Hydrocodone is a prescription opioid analgesic used to manage moderate to severe pain and, in some formulations, to suppress persistent cough. It belongs to the opioid (narcotic) class of medications and works by altering how the brain and nervous system respond to pain.

What Is Hydrocodone Used For?

Hydrocodone is commonly prescribed for:

• Acute pain after surgery or injury

• Chronic pain when non-opioid medications are ineffective

• Severe dental pain

• Pain related to cancer or major trauma

• Cough suppression (in combination products)

It is often combined with other medications such as:

• Acetaminophen (e.g., hydrocodone/APAP)

• Ibuprofen

• Antihistamines or cough suppressants

How Hydrocodone Works

Hydrocodone binds to mu-opioid receptors in the brain and spinal cord. This action:

• Reduces pain signals sent to the brain

• Alters emotional response to pain

• Produces a calming or sedative effect

Because of this mechanism, hydrocodone can also cause euphoria, which contributes to its potential for misuse.

Common Brand and Generic Forms

Hydrocodone is available under various brand and generic names, including:

• Extended-release tablets

• Immediate-release tablets

• Oral solutions

• Combination pain medications

Dosage and formulation depend on pain severity, patient history, and medical supervision.

Side Effects

Common side effects may include:

• Drowsiness or sedation

• Nausea and vomiting

• Constipation

• Dizziness

• Dry mouth

Serious side effects can include:

• Respiratory depression (slow or shallow breathing)

• Low blood pressure

• Confusion or loss of consciousness

• Dependence or addiction

Immediate medical attention is required if breathing problems or overdose symptoms occur.

Risks and Safety Considerations

• Hydrocodone carries a high risk of dependence and addiction

• Long-term use can lead to tolerance, requiring higher doses

• Mixing with alcohol, benzodiazepines, or other sedatives increases overdose risk

• Not recommended for individuals with severe respiratory conditions without close monitoring

Patients should take hydrocodone only as prescribed by a licensed healthcare provider.

Legal Status

Hydrocodone is classified as a Schedule II controlled substance in the United States. This means:

• It has accepted medical use

• It has a high potential for abuse

• Prescriptions are strictly regulated

Unauthorized use, sharing, or distribution is illegal.

Important Notes

• Do not stop hydrocodone abruptly without medical guidance, as withdrawal symptoms may occur

• Safe storage is essential to prevent misuse by others

• Regular follow-ups are important during treatment