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Percocet is a prescription medication that combines oxycodone, an opioid pain reliever, with acetaminophen, a non-opioid analgesic. It is used to manage moderate to severe pain, particularly after surgery, injury, or in conditions where other pain relievers are insufficient. Oxycodone works by altering pain perception in the brain and spinal cord, while acetaminophen enhances pain relief and can help reduce fever.

Typical adult dosages depend on the formulation and medical evaluation. Immediate-release Percocet is often prescribed at 2.5 mg to 10 mg of oxycodone combined with 325 mg of acetaminophen every 4–6 hours as needed, while extended-release forms may be taken once or twice daily under strict medical supervision. Because Percocet is an opioid, it carries risks such as drowsiness, respiratory depression, dependence, and overdose if misused. Alcohol and sedatives should be avoided. Always follow a licensed healthcare provider’s guidance to ensure safe and effective pain management.