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Phentermine is a prescription medication used primarily as an appetite suppressant to aid in weight loss for individuals who are overweight or obese and have weight-related health conditions such as high blood pressure, diabetes, or high cholesterol. It works by stimulating the central nervous system, which increases heart rate and blood pressure and reduces appetite. Phentermine is usually prescribed short-term in combination with diet and exercise programs.

Dosage of phentermine depends on the patient’s age, weight, and medical history. For adults, typical doses range from 15 mg to 37.5 mg once daily, usually taken in the morning to avoid insomnia. Extended-release formulations are sometimes used and should be taken as directed by a healthcare provider. It is important not to exceed the prescribed dose, as higher doses increase the risk of serious cardiovascular side effects.

There are significant warnings associated with phentermine use. It should not be taken by individuals with a history of heart disease, high blood pressure, stroke, hyperthyroidism, or glaucoma. Phentermine can also interact with other stimulant medications or monoamine oxidase inhibitors (MAOIs), leading to dangerous effects. Misuse or prolonged use may result in dependence or tolerance, and the medication is generally intended for short-term use (a few weeks).

Common side effects of phentermine include increased heart rate, elevated blood pressure, insomnia, nervousness, dry mouth, and constipation. Less common but more serious side effects can include chest pain, shortness of breath, swelling in the legs, or mental/mood changes such as agitation or confusion. Patients should monitor for cardiovascular symptoms and report any unusual side effects to their healthcare provider immediately.