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Percocet is a prescription pain medication that combines oxycodone, an opioid analgesic, with acetaminophen, a non-opioid pain reliever. It is commonly prescribed for moderate to severe pain, such as pain following surgery, injury, or certain medical procedures. Oxycodone works by binding to opioid receptors in the brain to reduce the perception of pain, while acetaminophen enhances overall pain relief.

The recommended dosage of Percocet depends on the strength of the tablet, the patient’s pain level, and prior opioid use. Typical adult doses range from 1 tablet every 4–6 hours as needed, with oxycodone strengths commonly between 2.5 mg and 10 mg combined with 325 mg of acetaminophen. Patients should never exceed the prescribed dose, especially because too much acetaminophen can cause serious liver damage. It is important to carefully track total daily acetaminophen intake from all sources.

Common side effects of Percocet include drowsiness, dizziness, nausea, vomiting, constipation, and dry mouth. Some individuals may also experience headache, itching, or lightheadedness. More serious side effects include slow or shallow breathing, low blood pressure, confusion, and severe sedation, which require immediate medical attention. Long-term use may result in tolerance, physical dependence, or addiction.

There are important warnings associated with Percocet use. It carries boxed warnings for addiction, abuse, and misuse, which can lead to overdose and death. Combining Percocet with alcohol, benzodiazepines, or other central nervous system depressants greatly increases the risk of respiratory depression. Percocet should be used cautiously in individuals with liver disease, lung conditions, or a history of substance abuse. Pregnant or breastfeeding individuals should only use Percocet under close medical supervision to ensure safe use.