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Oxycodone is a prescription opioid medication used to manage moderate to severe pain. It works by binding to opioid receptors in the brain and spinal cord, altering the perception of pain and increasing pain tolerance. Oxycodone is available in immediate-release forms for short-term pain control and extended-release forms for chronic pain that requires continuous relief. Because it is a potent opioid, oxycodone carries a risk of dependence, addiction, and overdose.

The appropriate dosage of oxycodone depends on the patient’s pain severity, opioid tolerance, and overall health condition. Immediate-release tablets are typically prescribed at 5 mg to 15 mg every 4–6 hours as needed, while extended-release tablets are taken once or twice daily. Doses should never be increased or altered without a doctor’s guidance, as misuse can lead to life-threatening respiratory depression. Tablets should be swallowed whole and not crushed or chewed, especially the extended-release forms.

Common side effects of oxycodone include drowsiness, dizziness, nausea, vomiting, constipation, dry mouth, and headache. Some patients may experience sweating, itching, or mood changes. Serious side effects can include slow or shallow breathing, low blood pressure, confusion, and loss of consciousness, which require immediate medical attention. Long-term use may lead to tolerance, physical dependence, or addiction.

There are significant warnings associated with oxycodone use. It carries boxed warnings for addiction, abuse, and life-threatening respiratory depression. Combining oxycodone with alcohol, benzodiazepines, or other central nervous system depressants can be fatal. Patients with lung disease, liver or kidney problems, or a history of substance abuse should use oxycodone cautiously. Pregnant or breastfeeding individuals should only use oxycodone under strict medical supervision. Regular medical monitoring is essential to ensure safe and effective use.