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Hydrocodone is a prescription opioid medication commonly used to treat moderate to severe pain and, in some formulations, to suppress cough. It works by binding to opioid receptors in the brain and spinal cord, reducing the sensation of pain and altering the body’s response to discomfort. Hydrocodone is often combined with other medications such as acetaminophen or ibuprofen to enhance pain relief, but this also increases the risk of certain side effects.

The appropriate dosage of hydrocodone depends on the formulation, patient tolerance, and severity of pain. Typical adult doses for pain range from 5 mg to 10 mg every 4–6 hours as needed, depending on the product prescribed. Extended-release versions are taken less frequently and should be swallowed whole, not crushed or chewed. Patients should follow their doctor’s instructions carefully, as taking higher doses or using the medication longer than prescribed increases the risk of dependence and overdose.

Common side effects of hydrocodone include drowsiness, dizziness, nausea, vomiting, constipation, and dry mouth. Some individuals may experience headache, itching, or lightheadedness. More serious side effects can include slow or shallow breathing, low blood pressure, confusion, and extreme sedation, which require immediate medical attention. Long-term use may lead to tolerance, meaning higher doses are needed to achieve the same effect.

There are important warnings associated with hydrocodone use. It carries a boxed warning for addiction, abuse, and misuse, which can result in overdose or death. Combining hydrocodone with alcohol, benzodiazepines, or other central nervous system depressants significantly increases the risk of respiratory depression. Hydrocodone should be used cautiously in individuals with lung disease, head injury, or liver problems, and it is generally not recommended during pregnancy or breastfeeding without strict medical supervision. Regular monitoring by a healthcare provider is essential to ensure safe and effective use.